MALIGNANT MELANOMA Prof. Camillo O. DI CICCO, M.D. ============================================================== Melanoma is the most aggressive of malignant cutaneous tumours. Because cases presenting with lymphonode involvement and distant metastases carry a very poor prognosis (50% and 20% respectively alive in 5 years) while on the contrary those presenting without evident lymphonode involvement have a much better survival (60% alive in 5 years). Survival is moreover directly related to the depth of tumour invasion: Melanoma thickness - 10 yr survival < 1.0 mm. - 90% 1.0 / 1.49 mm. - 78% 1.50 / 4.00 mm. - 65% > 4.00 mm. - 40% It is therefore extremely important a malignant melanoma early diagnosis according to the ABCD rules listed on page 3. The purpose of this site is to make know (health care professionals and visitors) the most important works reported worldwide on malignant melanoma.

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